GeneTex
United States (US)

Dispatched A antibody

Anti-Dispatched A antibody used in IHC (Paraffin sections) (IHC-P). GTX31465
Anti-Dispatched A antibody used in Western Blot (WB). GTX31465
Anti-Dispatched A antibody used in IHC (Paraffin sections) (IHC-P). GTX31465

Cat No. GTX31465

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

171 kDa. ( Note )

Positive Control

Human Kidney Tissue Slide , 3T3 Cell Lysate

Specificity/Sensitivity

At least two isoforms of DISP1 are known to exist; this antibody will detect both isoforms. DISP1 antibody is predicted to not cross-react with EMX1.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Dispatched A antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human Dispatched A.The immunogen is located within amino acids 20 - 70 of Dispatched A.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dispatched Rnd Transporter Family Member 1,Dispa,Disp1

Background

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
Anti-Dispatched A antibody used in IHC (Paraffin sections) (IHC-P). GTX31465

GTX31465 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31465 Dispatched A antibody.
Working concentration : 2.5 μg/ml

Anti-Dispatched A antibody used in Western Blot (WB). GTX31465

GTX31465 WB Image

WB analysis of 3T3 cell lysate using GTX31465 Dispatched A antibody.
Working concentration : 1 μg/ml

Anti-Dispatched A antibody used in IHC (Paraffin sections) (IHC-P). GTX31465

GTX31465 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31465 Dispatched A antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329