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Dopamine Receptor D2 antibody

Anti-Dopamine Receptor D2 antibody used in Western Blot (WB). GTX17570
Anti-Dopamine Receptor D2 antibody used in Western Blot (WB). GTX17570
Anti-Dopamine Receptor D2 antibody used in IHC (Paraffin sections) (IHC-P). GTX17570

Cat. No. GTX17570

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Dopamine Receptor D2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1000
IHC-P 1:50-400
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human Dopamine Receptor D2(214-260).

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_2887568

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dopamine receptor D2 , D2DR , D2R

Cellular Localization

Cell membrane

Background

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Dopamine Receptor D2 antibody used in Western Blot (WB). GTX17570

GTX17570 WB Image

WB analysis of U251 cell lysate using GTX17570 Dopamine Receptor D2 antibody.
Dilution : 1:300

Anti-Dopamine Receptor D2 antibody used in Western Blot (WB). GTX17570

GTX17570 WB Image

WB analysis of mouse brain tissue lysate using GTX17570 Dopamine Receptor D2 antibody.
Dilution : 1:300
Loading : 40μg

Anti-Dopamine Receptor D2 antibody used in IHC (Paraffin sections) (IHC-P). GTX17570

GTX17570 IHC-P Image

IHC-P analysis of rat brain tissue using GTX17570 Dopamine Receptor D2 antibody.
Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min
Dilution : 1:400

REFERENCE

Application Reference

Kaushik P et al. Life Sci 2020; 261 : 118349 Post-ischemic administration of dopamine D2 receptor agonist reduces cell death by activating mitochondrial pathway following ischemic stroke.
Application : IHC-P
Reactivity : Rat
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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399