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Dopamine beta Hydroxylase antibody, N-Term

Anti-Dopamine beta Hydroxylase antibody, N-Term used in Western Blot (WB). GTX82707

Cat. No. GTX82707

Host

 Sheep

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Primate
Package
100 μl ($499)
See all Dopamine beta Hydroxylase products

APPLICATION

Application Note

Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

69 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dopamine beta-hydroxylase , DBM , ORTHYP1

Cellular Localization

Secreted

Background

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Dopamine beta Hydroxylase antibody, N-Term used in Western Blot (WB). GTX82707

GTX82707 WB Image

Western blot of 20 ug of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein using Dopamine @-Hydroxylase antibody, N-Term (GTX82707).

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SDS
Glycerol.pdf
Package List Price ($)
$ 499