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Dysferlin antibody (Ready-to-use)

Anti-Dysferlin antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15109
Anti-Dysferlin antibody (Ready-to-use) used in Immunohistochemistry (IHC). GTX15109
Anti-Dysferlin antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15109

Cat. No. GTX15109

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, IHC

Reactivity

 Human
Package
7 ml ($399)
See all Dysferlin products

APPLICATION

Application Note

IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

237 kDa. ( Note )

Positive Control

Skeletal muscle

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dysferlin , FER1L1 , LGMD2B , LGMDR2 , MMD1

Cellular Localization

Cell membrane

Background

The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-Dysferlin antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15109

GTX15109 IHC-P Image

Human Skeletal Muscle stained with anti-Dysferlin antibody (GTX15108)

Anti-Dysferlin antibody (Ready-to-use) used in Immunohistochemistry (IHC). GTX15109

GTX15109 IHC Image

Anti-Dysferlin antibody (Ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX15109

GTX15109 IHC-P Image

GTX15109 staining Dysferlin in human skeletal muscle by Immunohistochemistry (FFPE-sections).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399