APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:10–1:20 |
Note :
IHC-P
High temperature antigen unmasking technique. Standard ABC technique.
|
Not tested in other applications.
PROPERTIES
Form
Liquid
Buffer
Tissue culture supernatant
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Prokaryotic recombinant protein corresponding to a region of the rod domain of the human dystrophin molecule.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
dystrophin , BMD , CMD3B , DXS142 , DXS164 , DXS206 , DXS230 , DXS239 , DXS268 , DXS269 , DXS270 , DXS272 , MRX85
Cellular Localization
Cytoplasm, cytoskeleton
Background
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Database
Research Area
DATA IMAGES
|
GTX01888 IHC-P Image
IHC-P analysis of human skeletal muscle tissue using GTX01888 Dystrophin antibody [13H6]. Note membrane staining of normal muscle fibers (A) and reduced and variable staining of revertant muscle fibers (B).
|
REFERENCE
There are currently no references for Dystrophin antibody [13H6] (GTX01888). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Dystrophin antibody [13H6] (GTX01888). Be the first to share your experience with this product.