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Dystrophin antibody [34C5]

Cat. No. GTX01889

Host

Mouse

Clonality

Monoclonal

Clone Name

34C5

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
500 μl ($679)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:40–1:80

Note :

IHC-P
High temperature antigen unmasking technique using 1 mM EDTA (pH 8.0). Standard ABC technique.

Not tested in other applications.

Calculated MW

427 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to amino acids 321 to 494 of the dystrophin molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

dystrophin , BMD , CMD3B , DXS142 , DXS164 , DXS206 , DXS230 , DXS239 , DXS268 , DXS269 , DXS270 , DXS272 , MRX85

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Database

Research Area

REFERENCE

There are currently no references for Dystrophin antibody [34C5] (GTX01889). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Dystrophin antibody [34C5] (GTX01889). Be the first to share your experience with this product.
Package List Price ($)
$ 679