*Optimal dilutions/concentrations should be determined by the researcher.
Freeze specimen tissue blocks in isopentane chilled in liquid nitrogen.
Not tested in other applications.
This antibody reacts strongly with the carboxy terminus (between amino acids 3669 and 3685) of human dystrophin.No cross-reactivity with mdx mouse tissue. Cross reacts very weakly with pig dystrophin.
Tissue culture supernatant
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
>32.4 μg/ml (Please refer to the vial label for the specific concentration.)
Synthetic polypeptide consisting of the last 17 amino acids at the carboxy terminus of the human dystrophin sequence.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
dystrophin , BMD , CMD3B , DXS142 , DXS164 , DXS206 , DXS230 , DXS239 , DXS268 , DXS269 , DXS270 , DXS272 , MRX85
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]