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Dystrophin antibody [MANDYS8]

Anti-Dystrophin antibody [MANDYS8] used in IHC (Frozen sections) (IHC-Fr). GTX27163
Anti-Dystrophin antibody [MANDYS8] used in IHC (Frozen sections) (IHC-Fr). GTX27163

Cat. No. GTX27163

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MANDYS8

Isotype

 IgG2b

Application

 WB, ICC/IF, IHC-Fr, ELISA

Reactivity

 Human, Mouse, Rat, Rabbit, Chicken, Pig
Package
100 μl ($399)
See all Dystrophin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr 1:400
ELISA Assay dependent
Not tested in other applications.

Calculated MW

427 kDa. ( Note )

Positive Control

human muscle

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

recombinant human dystrophin fragment.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_386028

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

dystrophin , BMD , CMD3B , DXS142 , DXS164 , DXS206 , DXS230 , DXS239 , DXS268 , DXS269 , DXS270 , DXS272 , MRX85

Cellular Localization

Cytoplasm, cytoskeleton

Background

The rod domain of the human dystrophin molecule is present in normal muscle tissue and in nearly all Becker muscular dystrophies. It is absent in the cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx).

Database

Research Area

DATA IMAGES

Anti-Dystrophin antibody [MANDYS8] used in IHC (Frozen sections) (IHC-Fr). GTX27163

GTX27163 IHC-Fr Image

IHC-Fr analysis of acetone-fixed human tongue tissue using GTX27163 Dystrophin antibody [MANDYS8] at 1:400.

Anti-Dystrophin antibody [MANDYS8] used in IHC (Frozen sections) (IHC-Fr). GTX27163

GTX27163 IHC-Fr Image

IHC-Fr analysis of acetone-fixed human tongue tissue using GTX27163 Dystrophin antibody [MANDYS8] at 1:400.

REFERENCE

Application Reference

Veltrop M et al. PLoS One 2018; 13 (2) : e0193289 A dystrophic Duchenne mouse model for testing human antisense oligonucleotides.

Clone Reference

Chengzu Long et al. Sci Adv . 2018; 4 (1) Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
Application : ICC/IF
Reactivity : Human
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399