APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:200 |
Note :
IHC-P
Heat-induced epitope retrieval (HIER) at pH 6 for 10 - 30 minutes
|
Not tested in other applications.
Calculated MW
Positive Control
Breast
PROPERTIES
Form
Liquid
Buffer
Tris, 1% BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant Human E-cadherin protein.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Cadherin 1 , Arc-1 , Bcds1 , Cd324 , Cdhe , Ecad , Lcam , Uvo , Cdh1
Background
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
Research Area
DATA IMAGES
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GTX57174 IHC-P Image
IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (10X)
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GTX57174 IHC-P Image
IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (40X)
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GTX57174 IHC-P Image
IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (20X)
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REFERENCE
There are currently no references for E-Cadherin antibody [IHC564] (GTX57174). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for E-Cadherin antibody [IHC564] (GTX57174). Be the first to share your experience with this product.