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E-Cadherin antibody [IHC564]

Anti-E-Cadherin antibody [IHC564] used in IHC (Paraffin sections) (IHC-P). GTX57174
Anti-E-Cadherin antibody [IHC564] used in IHC (Paraffin sections) (IHC-P). GTX57174
Anti-E-Cadherin antibody [IHC564] used in IHC (Paraffin sections) (IHC-P). GTX57174

Cat. No. GTX57174

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IHC564

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all E-Cadherin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Heat-induced epitope retrieval (HIER) at pH 6 for 10 - 30 minutes
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

Positive Control

Breast

PROPERTIES

Form

Liquid

Buffer

Tris, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human E-cadherin protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Cadherin 1 , Arc-1 , Bcds1 , Cd324 , Cdhe , Ecad , Lcam , Uvo , Cdh1

Background

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]

Research Area

DATA IMAGES

Anti-E-Cadherin antibody [IHC564] used in IHC (Paraffin sections) (IHC-P). GTX57174

GTX57174 IHC-P Image

IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (10X)

Anti-E-Cadherin antibody [IHC564] used in IHC (Paraffin sections) (IHC-P). GTX57174

GTX57174 IHC-P Image

IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (40X)

Anti-E-Cadherin antibody [IHC564] used in IHC (Paraffin sections) (IHC-P). GTX57174

GTX57174 IHC-P Image

IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (20X)

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399