GeneTex
  • Country / Location Selection

United States (US)

E-Cadherin antibody [RM244]

Anti-E-Cadherin antibody [RM244] used in IHC (Paraffin sections) (IHC-P). GTX33614
Anti-E-Cadherin antibody [RM244] used in Western Blot (WB). GTX33614

Cat No. GTX33614

Host

Rabbit

Clonality

Monoclonal

Clone Name

RM244

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 0.09% sodium azide, 50% Glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A peptide corresponding to Cadherin-1

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Arc1,CD324,CDH1,CDHE,ECAD,LCAM,UVO,cadherin 1,E-Cadherin,Cadherin 1

Cellular Localization

Cell junction,Cell membrane,Endosome,Golgi apparatus,trans-Golgi network

Background

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-E-Cadherin antibody [RM244] used in IHC (Paraffin sections) (IHC-P). GTX33614

GTX33614 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX33614 E-Cadherin antibody [RM244].
Dilution : 1:1000

Anti-E-Cadherin antibody [RM244] used in Western Blot (WB). GTX33614

GTX33614 WB Image

WB analysis of MCF-7 cell lysates using GTX33614 E-Cadherin antibody [RM244].
Dilution : 1:1000

REFERENCE

There are currently no references for E-Cadherin antibody [RM244] (GTX33614). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for E-Cadherin antibody [RM244] (GTX33614). Be the first to share your experience with this product.
Package List Price ($)
$ 329