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EAAT2 antibody

Anti-EAAT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37432
Anti-EAAT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37432
Anti-EAAT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37432

Cat. No. GTX37432

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Rat
Package
100 μg ($399)
See all EAAT2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 111-190 amino acids of human EAAT2

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11176609

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 1 member 2 , EAAT2 , EIEE41 , GLT-1 , HBGT

Cellular Localization

Cell membrane

Background

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

Database

Research Area

DATA IMAGES

Anti-EAAT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37432

GTX37432 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37432 EAAT2 antibody.
Fixation : 4% PFA
Antigen retireval : boiling with citrate buffer
Dilution : 1:200

Anti-EAAT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37432

GTX37432 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37432 EAAT2 antibody.
Dilution : 1:200

Anti-EAAT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37432

GTX37432 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37432 EAAT2 antibody.
Fixation : 4% PFA
Antigen retireval : boiling with citrate buffer
Dilution : 1:200

REFERENCE

Application Reference

Li RQ et al. Neural Regen Res 2018; 13 (6) : 1013-1018 Catgut implantation at acupoints increases the expression of glutamate aspartate transporter and glial glutamate transporter-1 in the brain of rats with spasticity after stroke.
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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399