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ECM1 antibody [ECM1/2889R]

Anti-ECM1 antibody [ECM1/2889R] used in IHC (Paraffin sections) (IHC-P). GTX02627

Cat. No. GTX02627

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 ECM1/2889R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Rat
Package
100 μg ($529)
See all ECM1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Product Note

This antibody reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human full-length ECM1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

extracellular matrix protein 1 , URBWD

Background

This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-ECM1 antibody [ECM1/2889R] used in IHC (Paraffin sections) (IHC-P). GTX02627

GTX02627 IHC-P Image

IHC-P analysis of human colon carcinoma section using GTX02627 ECM1 antibody [ECM1/2889R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529