Form
Liquid
Buffer
0.2 mg Na₂HPO₄, 0.9 mg NaCl, 5 mg BSA
Preservative
0.05 mg Thimerosal, 0.05 mg Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human EDA, identical to the related mouse and rat sequences.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
ectodysplasin A , ECTD1 , ED1 , ED1-A1 , ED1-A2 , EDA-A1 , EDA-A2 , EDA1 , EDA2 , HED , HED1 , ODT1 , STHAGX1 , TNLG7C , XHED , XLHED
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area