Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide (KLH conjugated) - Immunogen sequence information is commercially sensitive. Peptide sequence identity/similarity to Mouse: 93/100%. Rat: 93/100%.
Affinity purified with antigen
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Sphingosine-1-Phosphate Receptor 1,Ai849002,Edg1,Lpb1,S1P,S1P1,S1Pr1
EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG-1 leads to increased cell-cell aggregation and overexpression of cadherins. EDG-1 transcripts have been reported to be present in embryonic and adult brain, lung alveolar macrophages, vascular smooth muscle cells, endothelial cells, fibroblasts, melanocytes, and TAg-Jurkat T cells, but to be absent from breast cancer cell lines. ESTs have been isolated from brain, breast, heart, heart/melanocyte/uterus, kidney, liver, liver/spleen, lung, nerve, placenta, prostate, tonsil, uterus, and vessel libraries.