GeneTex
United States (US)

EDG2 antibody [C2C3], C-term

GTX108222_WB_19011507_932.jpg

Cat No. GTX108222

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Predict Reactivity

Mouse, Rat, Bovine, Chicken, Xenopus laevis, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human EDG2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

EDG2 antibody, GPR26 antibody, Gpcr26 antibody, LPA1 antibody, Mrec1.3 antibody, VZG1 antibody, edg-2 antibody, rec.1.3 antibody, vzg-1 antibody, LPAR1 antibody, lysophosphatidic acid receptor 1 antibody, ventricular zone gene 1 antibody, lysophosphatidic acid receptor Edg-2 antibody, LPA receptor 1 antibody, "endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 antibody", LPA-1 antibody

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX108222_WB_19011507_932.jpg

GTX108222 WB Image

Sample (30 ug of whole cell lysate)
A: 293T
B: H1299
10% SDS PAGE
GTX108222 diluted at 1:1000

Reference
SDS
Glycerol.pdf
Thimerosal.pdf