GeneTex
United States (US)

EDG5 antibody

EDG5-antibody__GTX87937-1_18122102_661.jpg

Cat No. GTX87937

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Specificity/Sensitivity

EDG5 Antibody detects endogenous levels of total EDG5 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human EDG5.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

S1P2, Sphingosine1phosphate receptor Edg5, Sphingosine 1-phosphate receptor Edg-5, S1P receptor Edg5, Sphingosine 1-phosphate receptor 2, Sphingosine1phosphate receptor2, S1P receptor Edg-5, Sphingosine, Endothelial differentiation G-protein coupled receptor 5, Endothelial differentiation Gprotein coupled receptor5, Endothelial differentiation Gprotein coupled receptor 5, EDG5, S1P receptor Edg 5

Background

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
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Database

Research Area

DATA IMAGES
EDG5-antibody__GTX87937-1_18122102_661.jpg

GTX87937 WB Image

Western blot analysis of extracts from COLO205 cells, using EDG5 antibody. The lane on the right is treated with the synthesized peptide.