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EDG8 antibody

Anti-EDG8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71425

Cat No. GTX71425

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Rat, Pig, Monkey, Bat
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 3 - 6 μg/ml
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Predict Reactivity

Mouse, Bovine, Dog, Hamster, Elephant, Gorilla, Marmoset(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human S1PR5 / EDG8.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

sphingosine-1-phosphate receptor 5 , EDG8 , Edg8 , S1P5 , S1PR5 , SPPR1 , SPPR2 , sphingosine1phosphate receptor 5

Cellular Localization

Cell membrane

Background

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-EDG8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71425

GTX71425 IHC-P Image

IHC-P analysis of rat brain, neurons and glia tissue using GTX71425 EDG8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf