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EED antibody

Anti-EED antibody used in Western Blot (WB). GTX33168

Cat. No. GTX33168

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP

Reactivity

 Human, Mouse
Package
100 μl ($419)
See all EED products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IP Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EED (NP_694536.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887700

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

embryonic ectoderm development , COGIS , HEED , WAIT1

Cellular Localization

Nucleus

Background

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-EED antibody used in Western Blot (WB). GTX33168

GTX33168 WB Image

WB analysis of various sample lysates using GTX33168 EED antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Su D et al. Nucleic Acids Res 2021; 49 (8) : 4421-4440 Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.
Application : WB
Reactivity : Human
Dongxue Su et al. bioRxiv 2019; (Epub) Bimodal Regulation of the PRC2 Complex by USP7 Underlies Melanomagenesis.
Application : WB, IP
Reactivity : Human
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419