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EFCAB4B antibody

Anti-EFCAB4B antibody used in IHC (Paraffin sections) (IHC-P). GTX85142
Anti-EFCAB4B antibody used in Western Blot (WB). GTX85142
Anti-EFCAB4B antibody used in IHC (Paraffin sections) (IHC-P). GTX85142

Cat. No. GTX85142

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all EFCAB4B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

Positive Control

Mouse Kidney Tissue Lysate(GTX27936) , Human Kidney Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

EFCAB4B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B.The immunogen is located within amino acids 640 - 690 of EFCAB4B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

calcium release activated channel regulator 2A , EFCAB4B

Cellular Localization

Cytoplasm

Background

EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.

Database

Research Area

DATA IMAGES

Anti-EFCAB4B antibody used in IHC (Paraffin sections) (IHC-P). GTX85142

GTX85142 IHC-P Image

IHC-P analysis of human kidney tissue using GTX85142 EFCAB4B antibody.
Working concentration : 10 μg/ml

Anti-EFCAB4B antibody used in Western Blot (WB). GTX85142

GTX85142 WB Image

WB analysis of mouse kidney tissue lysate using GTX85142 EFCAB4B antibody.
Working concentration : 1 μg/ml

Anti-EFCAB4B antibody used in IHC (Paraffin sections) (IHC-P). GTX85142

GTX85142 IHC-P Image

IHC-P analysis of human kidney tissue using GTX85142 EFCAB4B antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399