GeneTex
United States (US)

EFEMP1 antibody

Cat No. GTX14926

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IP
Reactivity Human, Rat
APPLICATION

Application Note

IP: Use at a dilution of 1/200. WB: Use at a dilution of 1/500. Detects a band of approximately 62 kDa (predicted molecular weight: 60 kDa). Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

55 kDa. ( Note )

Positive Control

Human RPE cell extracts.

Specificity/Sensitivity

The Anti EFEMP1 selective antibody was generated against a conserved sequence near the C terminal that is unique to EFEMP1 protein only. This antibody detects a strong 62 kDa EFEMP1 protein in human.
PROPERTIES

Form

Liquid

Buffer

Proprietay antibody stabilization buffer containing 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.25 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide: TYTQCTDGYEWDPVRQQC.

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Egf Containing Fibulin Extracellular Matrix Protein 1,Dhrd,Drad,Fbln3,Fbnl,Fibl-3,Mlvt,Mtlv,S1-5,Efemp1

Cellular Localization

Secreted

Background

This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Two transcripts with distinct 5' UTR have been described; the resulting proteins have distinct N-terminal amino acid sequences. Translation initiation from internal methionine residues was observed with in vitro translation. A signal peptide sequence is predicted for translation initiation sites 1, 2, and 4. The protein isoforms contain 5 or 6 calcium-binding EGF2 domains and 5 or 6 EGF2 domains. Mutations in this gene cause the retinal disease Malattia Leventinese.

Database

REFERENCE
Package List Price ($)
$ 319