GeneTex
  • Country / Location Selection

United States (US)

EGFR antibody [111.6]

Anti-EGFR antibody [111.6] used in IHC (Paraffin sections) (IHC-P). GTX73849

Cat No. GTX73849

Host

Mouse

Clonality

Monoclonal

Clone Name

111.6

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
1 ml ($569)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:25-1:50
Not tested in other applications.

Calculated MW

134 kDa. ( Note )

Specificity/Sensitivity

The antibody recognizes an epitope mapping in the extracellular domain of EGFR.

PROPERTIES

Form

Liquid

Buffer

PBS with <0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Pig

Immunogen

BALB/C mice were injected with extracellular domain of human recombinant EGFR protein.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

EGFR , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , epidermal growth factor receptor , mENA , EGF Receptor

Cellular Localization

Cell membrane,Endoplasmic reticulum membrane,Golgi apparatus membrane,Nucleus membrane,Endosome,Endosome membrane,Nucleus,Secreted

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Database

Research Area

DATA IMAGES

Anti-EGFR antibody [111.6] used in IHC (Paraffin sections) (IHC-P). GTX73849

GTX73849 IHC-P Image

IHC-P analysis of human placenta tissue using GTX73849 EGFR antibody [111.6].

REFERENCE

REVIEW

There are currently no reviews for EGFR antibody [111.6] (GTX73849). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf