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EGFR antibody [EGFR.113]

Anti-EGFR antibody [EGFR.113] used in IHC (Paraffin sections) (IHC-P). GTX01874

Cat. No. GTX01874

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 EGFR.113

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($749)
See all EGFR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:20

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

134 kDa. ( Note )

Product Note

This antibody recognizes external domain of the human epidermal growth factor receptor.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic fusion protein corresponding to the external domain of the epidermal growth factor receptor molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

epidermal growth factor receptor , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , mENA

Cellular Localization

Cell membrane , Endoplasmic reticulum membrane , Endosome , Endosome membrane , Nucleus

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Database

Research Area

DATA IMAGES

Anti-EGFR antibody [EGFR.113] used in IHC (Paraffin sections) (IHC-P). GTX01874

GTX01874 IHC-P Image

IHC-P analysis of human placenta tissue using GTX01874 EGFR antibody [EGFR.113].

REFERENCE

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REVIEW

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Package List Price ($)
$ 749