*Optimal dilutions/concentrations should be determined by the researcher.
|4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.
This antibody reacts with extracellular domain of human protein kinase EGFR (ErbB1 / HER1); epitope within amino acids 6-273.
This product does not react with Mouse.
PBS, 15mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Batch dependent (Please refer to the vial label for the specific concentration.)
Human epidermoid carcinoma line A431
Purified by size-exclusion chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
EGFR,ERBB,ERBB1,HER1,NISBD2,PIG61,epidermal growth factor receptor,mENA,EGF Receptor
Cell membrane,Endoplasmic reticulum membrane,Golgi apparatus membrane,Nucleus membrane,Endosome,Endosome membrane,Nucleus,Secreted
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]