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EGFR antibody [GFR/2600R]

Anti-EGFR antibody [GFR/2600R] used in IHC (Paraffin sections) (IHC-P). GTX02628
Anti-EGFR antibody [GFR/2600R] used in IHC (Paraffin sections) (IHC-P). GTX02628

Cat No. GTX02628

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GFR/2600R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($429)
See all EGFR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

134 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugate of human EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

epidermal growth factor receptor , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , mENA

Cellular Localization

Cell membrane , Endoplasmic reticulum membrane , Endosome , Endosome membrane , Nucleus

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Database

Research Area

DATA IMAGES

Anti-EGFR antibody [GFR/2600R] used in IHC (Paraffin sections) (IHC-P). GTX02628

GTX02628 IHC-P Image

IHC-P analysis of human placenta tissue section using GTX02628 EGFR antibody [GFR/2600R].

Anti-EGFR antibody [GFR/2600R] used in IHC (Paraffin sections) (IHC-P). GTX02628

GTX02628 IHC-P Image

IHC-P analysis of human squamous cell carcinoma lung cancer section using GTX02628 EGFR antibody [GFR/2600R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 429