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EGFR antibody [ICR10] (PE)

Cat No. GTX75350

Host

Rat

Clonality

Monoclonal

Clone Name

ICR10

Isotype

IgG2a

Application

ICC/IF, FACS

Reactivity

Human, Mouse
Package
50 test ($289)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Calculated MW

134 kDa. ( Note )

Specificity/Sensitivity

This antibody, clone ICR10 binds to epitope B from EGFR

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Extracellular domain of human EGF-receptor from head and neck carcinoma.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Epidermal Growth Factor Receptor , Erbb , Erbb1 , Her1 , Nisbd2 , Pig61 , Mena , Egfr

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Database

Research Area

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 289