GeneTex
United States (US)

EGFR antibody [SP9]

EGFR-antibody-SP9_IHC (Formalin-fixed paraffin-embedded sections)_GTX16671-1_18121410_125.jpg
EGFR-antibody-SP9_FACS_GTX16671-1_18121410_284.jpg
EGFR-antibody-SP9_IHC_GTX16671-1_18121410_958.jpg

Cat No. GTX16671

Host Rabbit
Clonality Monoclonal
Clone Name SP9
Application WB, IHC-P, FACS, IHC
Reactivity Human
APPLICATION

Application Note

IHC-P: 1/100. Antigen retrieval is not essential but may optimise staining. WB: 1/200. Predicted molecular weight: 134 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

134 kDa. ( Note )

Positive Control

Placenta and lung
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Synthetic peptide (Human) (C terminal).

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Epidermal Growth Factor Receptor,Erbb,Erbb1,Her1,Nisbd2,Pig61,Mena,Egfr

Cellular Localization

Cell Membrane and Secreted

Background

Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. EGFR over expression in tumors indicates poor prognosis. EGFR over expression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

Database

Research Area

DATA IMAGES
EGFR-antibody-SP9_IHC (Formalin-fixed paraffin-embedded sections)_GTX16671-1_18121410_125.jpg

GTX16671 IHC-P Image

Formalin fixed paraffin embedded human placenta stained with EGFR antibody (GTX16671)

EGFR-antibody-SP9_FACS_GTX16671-1_18121410_284.jpg

GTX16671 FACS Image

Flow cytometric analysis of rabbit anti-EGFR (SP9) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue)

EGFR-antibody-SP9_IHC_GTX16671-1_18121410_958.jpg

GTX16671 IHC Image

Human placenta stained with anti-Epidermal Growth Factor Receptor (EGFR) antibody

Package List Price ($)
$ 329