GeneTex

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United States (US)

EGFR antibody

Cat. No. GTX77610

Host

 Mouse

Clonality

 Monoclonal

Isotype

 IgG2b

Application

 WB, ICC/IF, IHC-Fr, FACS, IP

Reactivity

 Human, Horse
Package
100 μg ($399)
See all EGFR products

APPLICATION

Application Note

Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

134 kDa. ( Note )

Product Note

This antibody does not react with erbB-2, erbB-3 and erbB-4.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human epidermoid carcinoma line A431; epitope mapped between aa 6-273 of human EGFR

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_384605

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

epidermal growth factor receptor , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , mENA

Cellular Localization

Cell membrane , Endoplasmic reticulum membrane , Endosome , Endosome membrane , Nucleus

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399