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ELOVL6 antibody

Anti-ELOVL6 antibody used in Western Blot (WB). GTX85403
Anti-ELOVL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85403
Anti-ELOVL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85403

Cat. No. GTX85403

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all ELOVL6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ELOVL6 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ELOVL6.The immunogen is located within the first 50 amino acids of ELOVL6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ELOVL fatty acid elongase 6 , FACE , FAE , LCE

Cellular Localization

Endoplasmic reticulum membrane

Background

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Database

Research Area

DATA IMAGES

Anti-ELOVL6 antibody used in Western Blot (WB). GTX85403

GTX85403 WB Image

WB analysis of human brain tissue lysate using GTX85403 ELOVL6 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-ELOVL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85403

GTX85403 IHC-P Image

IHC-P analysis of human brain tissue using GTX85403 ELOVL6 antibody.
Working concentration : 5 μg/ml

Anti-ELOVL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85403

GTX85403 IHC-P Image

IHC-P analysis of human brain tissue using GTX85403 ELOVL6 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399