APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 3 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Dog, Elephant, Marmoset, Orangutan(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 15 amino acid peptide from N-terminal extracellular domain of human EMR3.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
adhesion G protein-coupled receptor E3 , ADGRE3 , EMR3 , adhesion G proteincoupled receptor E3
Cellular Localization
Cell membrane,Secreted,Extracellular space
Background
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
Database
Research Area
DATA IMAGES
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GTX12974 IHC-P Image
IHC-P analysis of human lymph node, non-hodgkins lymphoma tissue using GTX12974 EMR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12974 IHC-P Image
IHC-P analysis of human ovary, carcinoma tissue using GTX12974 EMR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12974 IHC-P Image
IHC-P analysis of brain, glioblastoma tissue using GTX12974 EMR3 antibody.
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GTX12974 IHC-P Image
IHC-P analysis of brain, hippocampus, ca4 neurons tissue using GTX12974 EMR3 antibody.
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GTX12974 IHC-P Image
IHC-P analysis of brain, alzheimer's, senile plaque tissue using GTX12974 EMR3 antibody.
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GTX12974 IHC-P Image
IHC-P analysis of human spleen, lymphocytes tissue using GTX12974 EMR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
There are currently no references for EMR3 antibody (GTX12974). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for EMR3 antibody (GTX12974). Be the first to share your experience with this product.
