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EP300 antibody [3G230]

Anti-EP300 antibody [3G230] used in Western Blot (WB). GTX14984

Cat. No. GTX14984

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3G230

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IP

Reactivity

 Human
Package
25 μg ($399)
See all EP300 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1μg/ml
ICC/IF Assay dependent
IHC-P 1-5μg/ml
IP Assay dependent

Note :

IHC-P
Antigen retireval : Requires HIER pretreatment
Not tested in other applications.

Calculated MW

264 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse,Rat samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human p300 protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

E1A binding protein p300 , EP300 , KAT3B , RSTS2 , p300

Cellular Localization

Cytoplasm,Nucleus,Chromosome

Background

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-EP300 antibody [3G230] used in Western Blot (WB). GTX14984

GTX14984 WB Image

WB analysis of A431 cell lysate using GTX14984 EP300 antibody [3G230].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399