GeneTex
United States (US)

EPO receptor antibody

GTX32590_20180530_IHC-P_18121410_408.jpg
GTX32590_20180530_WB_18121410_576.jpg
GTX32590_20180530_IHC-P_1_18121410_819.jpg

Cat No. GTX32590

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

55 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 274-508 of human EPOR (NP_000112.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Erythropoietin Receptor,Epo-R,Epor

Background

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES
GTX32590_20180530_IHC-P_18121410_408.jpg

GTX32590 IHC-P Image

IHC-P analysis of human prostate tissue using GTX32590 EPO receptor antibody.
Dilution : 1:100

GTX32590_20180530_WB_18121410_576.jpg

GTX32590 WB Image

WB analysis of various samples using GTX32590 EPO receptor antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32590_20180530_IHC-P_1_18121410_819.jpg

GTX32590 IHC-P Image

IHC-P analysis of human trachea tissue using GTX32590 EPO receptor antibody.
Dilution : 1:100