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EPO receptor antibody

Anti-EPO receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32590
Anti-EPO receptor antibody used in Western Blot (WB). GTX32590
Anti-EPO receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32590
Anti-EPO receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32590

Cat. No. GTX32590

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all EPO receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 274-508 of human EPOR (NP_000112.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

erythropoietin receptor , EPO-R

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-EPO receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32590

GTX32590 IHC-P Image

IHC-P analysis of human trachea tissue using GTX32590 EPO receptor antibody.
Dilution : 1:100

Anti-EPO receptor antibody used in Western Blot (WB). GTX32590

GTX32590 WB Image

WB analysis of various sample lysates using GTX32590 EPO receptor antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-EPO receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32590

GTX32590 IHC-P Image

IHC-P analysis of human prostate tissue using GTX32590 EPO receptor antibody.
Dilution : 1:100

Anti-EPO receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32590

GTX32590 IHC-P Image

IHC-P analysis of mouse fetal tissue using GTX32590 EPO receptor antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399