GeneTex
United States (US)

EPO receptor antibody

GTX37704_20190129_IHC-P_1_19012901_621.jpg
GTX37704_20190129_IHC-Fr_19012901_894.jpg
GTX37704_20190129_WB_19012901_827.jpg
GTX37704_20190129_IHC-P_19012901_701.jpg

Cat No. GTX37704

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-Fr
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:200-1000
IHC-P 1:100-500
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

55 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

10 mM PBS, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human EPOR. Please contact us for the exact immunogen sequence.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Erythropoietin Receptor,Epo-R,Epor

Cellular Localization

Cell membrane,Secreted

Background

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES
GTX37704_20190129_IHC-P_1_19012901_621.jpg

GTX37704 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX37704 EPO receptor antibody.
Dilution : 2.5μg/ml

GTX37704_20190129_IHC-Fr_19012901_894.jpg

GTX37704 IHC-Fr Image

IHC-Fr analysis of human lung cancer tissue using GTX37704 EPO receptor antibody.
Dilution : 2.5μg/ml

GTX37704_20190129_WB_19012901_827.jpg

GTX37704 WB Image

WB analysis of rat thyroid (Lane 1), human thyroid cancer (Lane 2), human breast cancer (Lane 3), human lung cancer (Lane 4), U251 cell (Lane 5) lysates using GTX37704 EPO receptor antibody.
Dilution : 1μg/ml

GTX37704_20190129_IHC-P_19012901_701.jpg

GTX37704 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX37704 EPO receptor antibody.
Dilution : 2.5μg/ml