GeneTex
United States (US)

ERAB antibody [10D12]

Cat No. GTX10259

Host Mouse
Clonality Monoclonal
Clone Name 10D12
Isotype IgG2b
Application WB, IHC-Fr, Dot
Reactivity Human
APPLICATION

Application Note

Dot: Use at a dilution of 1/100 - 1/1000. IHC: Use at a dilution of 1/100 - 1/1000. WB: Use at a dilution of 1/100 - 1/1000. Predicted molecular weight: 27 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

27 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes the recombinant human ERAB protein (27kDa) and the endogenous ERAB protein in cell extracts in immunoblots and ELISA assays, with virtually no crossreactivity with other human proteins.
PROPERTIES

Form

Liquid

Buffer

Preservative: none; Constituents: PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant, full-length Human ERAB protein (Fusion protein).

Purification


Ammonium sulfate precipitated and dialyzed tissue culture supernatant.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ABAD, 300256, MHBD, 3028, 17bHSD10, HSD17B10, 17b-HSD10, HADH2, ERAB, Q99714, 17b HSD10

Cellular Localization

Mitochondrial

Background

ERAB (Endoplasmic Reticulum beta Amyloid Binding Protein) has been associated with beta Amyloid neurotoxicity. ERAB is an intracellular 27 kDa polypeptide which appears to be upregulated in the brains of Alzheimer’s Disease patients.

Database

Research Area

Package List Price ($)
$ 349