APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:2000 |
| 1:50-1:100 |
| 1:50 |
| 1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.89 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Full length human recombinant protein of human HSD17B10 (NP_004484) produced in HEK293T cell.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
hydroxysteroid 17-beta dehydrogenase 10 , 17b-HSD10 , ABAD , CAMR , DUPXp11.22 , ERAB , HADH2 , HCD2 , HSD10MD , MHBD , MRPP2 , MRX17 , MRX31 , MRXS10 , SCHAD , SDR5C1
Cellular Localization
Mitochondrion
Background
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Database
Research Area
DATA IMAGES
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/templates/default/js/lightbox/images/loading.gif "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
|
GTX84347 IHC-P Image
IHC-P analysis of human pancreas tissue using GTX84347 ERAB antibody [11A2].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
|
|
|
GTX84347 IHC-P Image
IHC-P analysis of human endometrium tissue using GTX84347 ERAB antibody [11A2].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
|
|
|
GTX84347 IHC-P Image
IHC-P analysis of human breast tissue using GTX84347 ERAB antibody [11A2].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
|
|
|
GTX84347 IHC-P Image
IHC-P analysis of human thyroid carcinoma tissue using GTX84347 ERAB antibody [11A2].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
|
|
|
GTX84347 ICC/IF Image
ICC/IF analysis of COS7 cells transiently transfected with ERAB plasmid using GTX84347 ERAB antibody [11A2].
|
|
|
GTX84347 FACS Image
FACS analysis of HeLa cells using GTX84347 ERAB antibody [11A2].
Red : Primary antibody
Blue : Negative control antibody
|
|
|
GTX84347 FACS Image
FACS analysis of Jurkat cells using GTX84347 ERAB antibody [11A2].
Red : Primary antibody
Blue : Negative control antibody
|
|
|
GTX84347 WB Image
WB analysis of HEK293T cells transfected with ERAB plasmid (Right) or empty vector (Left) for 48 hrs using GTX84347 ERAB antibody [11A2].
Loading : 5 ug per lane
|
|
|
GTX84347 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX84347 ERAB antibody [11A2].
|
REFERENCE
There are currently no references for ERAB antibody [11A2] (GTX84347). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for ERAB antibody [11A2] (GTX84347). Be the first to share your experience with this product.
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_2645_IHC-P_w_23061420_589.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_2644_IHC-P_w_23061420_208.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_2643_IHC-P_w_23061420_410.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_2642_IHC-P_w_23061420_473.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_1049_ICCIF_w_23061420_510.webp "Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347")
![Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_373_FACS_w_23061420_985.webp "Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347")
![Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_374_FACS_w_23061420_829.webp "Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347")
![Anti-ERAB antibody [11A2] used in Western Blot (WB). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_4299_WB_w_23061420_282.webp "Anti-ERAB antibody [11A2] used in Western Blot (WB). GTX84347")
![Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347](/upload/website/prouct_img/small/GTX84347/GTX84347_1050_ICCIF_w_23061420_313.webp "Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_2645_IHC-P_w_23061420_589.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_2644_IHC-P_w_23061420_208.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_2643_IHC-P_w_23061420_410.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_2642_IHC-P_w_23061420_473.webp "Anti-ERAB antibody [11A2] used in IHC (Paraffin sections) (IHC-P). GTX84347")
![Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_1049_ICCIF_w_23061420_510.webp "Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347")
![Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_373_FACS_w_23061420_985.webp "Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347")
![Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_374_FACS_w_23061420_829.webp "Anti-ERAB antibody [11A2] used in Flow cytometry (FACS). GTX84347")
![Anti-ERAB antibody [11A2] used in Western Blot (WB). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_4299_WB_w_23061420_282.webp "Anti-ERAB antibody [11A2] used in Western Blot (WB). GTX84347")
![Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347](/upload/website/prouct_img/normal/GTX84347/GTX84347_1050_ICCIF_w_23061420_313.webp "Anti-ERAB antibody [11A2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84347")