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ERAB antibody

Anti-ERAB antibody used in Western Blot (WB). GTX48613

Cat No. GTX48613

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Zebrafish
Package
50 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-2μg/ml
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX48613-PEP).

Specificity/Sensitivity

This antibody is expected to recognise both reported isoforms.

Predict Reactivity

Mouse, Rat, Bovine, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence CIRLDGAIRMQP, from the C Terminus of the protein sequence according to NP_004484.1; NP_001032900.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Hydroxysteroid 17-Beta Dehydrogenase 10 , 17B-Hsd10 , Abad , Camr , Dupxp11.22 , Erab , Hadh2 , Hcd2 , Hsd10Md , Mhbd , Mrpp2 , Mrx17 , Mrx31 , Mrxs10 , Schad , Sdr5C1 , Hsd17B10

Background

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]

Database

Research Area

DATA IMAGES

Anti-ERAB antibody used in Western Blot (WB). GTX48613

GTX48613 WB Image

WB analysis of human brain lysate using GTX48613 ERAB antibody.
Dilution : 0.3μg/ml
Loading : 30μg protein in RIPA buffer

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf