GeneTex
United States (US)

ERAP1 antibody

GTX31553_2738_WB_20180221_18121410_191.jpg
GTX31553_1171_IHC-P_20180221_18121410_708.jpg
GTX31553_1170_IHC-P_20180221_18121410_946.jpg

Cat No. GTX31553

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

107 kDa. ( Note )

Positive Control

SK-N-SH Cell Lysate(GTX23956)

Specificity/Sensitivity

At least two isoforms of ERAP1 are known to exist; this antibody will detect both isoforms. ERAP1 antibody is predicted to not cross-react with ERAP2.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ERAP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERAP.The immunogen is located within amino acids 730 - 780 of ERAP1 .

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Endoplasmic Reticulum Aminopeptidase 1,A-Lap,Alap,Appils,Arts-1,Arts1,Eraap,Eraap1,Pils-Ap,Pilsap,Erap1

Background

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

Database

Research Area

DATA IMAGES
GTX31553_2738_WB_20180221_18121410_191.jpg

GTX31553 WB Image

WB analysis of SK-N-SH cell lysate using GTX31553 ERAP1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX31553_1171_IHC-P_20180221_18121410_708.jpg

GTX31553 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31553 ERAP1 antibody.
Working concentration : 20 μg/ml

GTX31553_1170_IHC-P_20180221_18121410_946.jpg

GTX31553 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31553 ERAP1 antibody.
Working concentration : 5 μg/ml