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ERAP1 antibody

Anti-ERAP1 antibody used in Western Blot (WB). GTX66660
Anti-ERAP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX66660

Cat. No. GTX66660

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all ERAP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

107 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 435-489 of Human ERAP1.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

endoplasmic reticulum aminopeptidase 1 , A-LAP , ALAP , APPILS , ARTS-1 , ARTS1 , ERAAP , ERAAP1 , PILS-AP , PILSAP

Cellular Localization

Endoplasmic reticulum membrane

Background

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

Database

Research Area

DATA IMAGES

Anti-ERAP1 antibody used in Western Blot (WB). GTX66660

GTX66660 WB Image

WB analysis of various samples using GTX66660 ERAP1 antibody.
Lane1 : HepG2 whole cell lysate(40ug)
Lane2 : HEK293T whole cell lysate(20ug)
Lane3 : PC12 whole cell lysate(20ug)
Lane4 : AML-12 whole cell lysate(40ug)
Dilution : 1:500

Anti-ERAP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX66660

GTX66660 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66660 ERAP1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399