APPLICATION
Product Note
The peptide was used in the production of GTX17012.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-EEKPKKKKKAQEDL
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Protein Disulfide Isomerase Family A Member 3 , Er60 , Erp57 , Erp60 , Erp61 , Grp57 , Grp58 , Hel-S-269 , Hel-S-93N , Hst17083 , P58 , Pi-Plc , Pdia3
Background
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for ERp57 blocking peptide (GTX17012-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for ERp57 blocking peptide (GTX17012-PEP). Be the first to share your experience with this product.