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ETS1 antibody

Cat No. GTX11912

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Mouse, Rat, Rabbit
Package
50 μl ($299)

APPLICATION

Application Note

WB: Use at a dilution of 1/500 - 1/1000. Detects a band of approximately 54 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

50 kDa. ( Note )

Positive Control

CCRF-CEM nuclear extract

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2% Gelatin

Preservative

0.01% Thimerosal, 0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide: YENDYPSVILRDPL, corresponding to amino acids 201-214 of Human ETS1.

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ETS proto-oncogene 1, transcription factor , ETS-1 , EWSR2 , c-ets-1 , p54

Cellular Localization

Cytoplasm , Nucleus

Background

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299