APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Positive Control
HepG2 , Jurkat , Raji , NCI-H929
Predict Reactivity
Mouse, Bovine, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.42 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human EXOSC8. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_10617882
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
exosome component 8 , CIP3 , EAP2 , OIP2 , PCH1C , RRP43 , Rrp43p , bA421P11.3 , p9
Cellular Localization
Cytoplasm , Nucleus , nucleolus
Background
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq]
Database
Research Area
DATA IMAGES
|
GTX118146 WB Image
Sample (30 ug of whole cell lysate)
A: HepG2
12% SDS PAGE
GTX118146 diluted at 1:1000
|
|
|
GTX118146 WB Image
EXOSC8 antibody detects EXOSC8 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with EXOSC8 antibody (GTX118146) diluted by 1:1000.
|
|
|
GTX118146 ICC/IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using EXOSC8(GTX118146) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.
|
REFERENCE
There are currently no references for EXOSC8 antibody (GTX118146). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for EXOSC8 antibody (GTX118146). Be the first to share your experience with this product.
