GeneTex
United States (US)

EXT2 antibody [N3C2], Internal

GTX101934_WB_19011506_182.jpg

Cat No. GTX101934

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

82 kDa. ( Note )

Positive Control

A549 , HeLa , Jurkat , NT2D1

Predict Reactivity

Mouse, Rat, Zebrafish, Bovine, Chicken, Xenopus laevis(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.57mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human EXT2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

SOTV antibody, EXT2 antibody, glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody, N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody, putative tumor suppressor protein EXT2 antibody, multiple exostoses protein 2 antibody, exostosin-2 antibody, exostosin 2 antibody

Cellular Localization

Endoplasmic reticulum membrane; Single-pass type II membrane protein , Golgi apparatus membrane; Single-pass type II membrane protein

Background

This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX101934_WB_19011506_182.jpg

GTX101934 WB Image

Sample (30 ug of whole cell lysate)
A: A549
B: Hela
7.5% SDS PAGE
GTX101934 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169