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EZH2 antibody [6A10]

Anti-EZH2 antibody [6A10] used in IHC (Paraffin sections) (IHC-P). GTX01878

Cat. No. GTX01878

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6A10

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($509)
See all EZH2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:200

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections.
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Product Note

This antibody recognizes a region common to isoforms A and B of the protein.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to a portion of the N-terminus domain of the human EZH2 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

enhancer of zeste 2 polycomb repressive complex 2 subunit , ENX-1 , ENX1 , EZH2b , KMT6 , KMT6A , WVS , WVS2

Cellular Localization

Nucleus

Background

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-EZH2 antibody [6A10] used in IHC (Paraffin sections) (IHC-P). GTX01878

GTX01878 IHC-P Image

IHC-P analysis of T-Cell lymphoma tissue using GTX01878 EZH2 antibody [6A10]. Note nuclear staining.

REFERENCE

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REVIEW

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Package List Price ($)
$ 509