APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1-2μg/ml for 30 min at RT |
| Assay dependent |
| Assay dependent |
|
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
|
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant full-length human Elastin protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ELN , SVAS , WBS , WS , elastin , Elastin
Cellular Localization
Secreted,Extracellular space,Extracellular matrix
Background
This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
![Anti-Elastin antibody [ELN/1981] used in IHC (Paraffin sections) (IHC-P). GTX17734](/templates/default/js/lightbox/images/loading.gif "Anti-Elastin antibody [ELN/1981] used in IHC (Paraffin sections) (IHC-P). GTX17734")
|
GTX17734 IHC-P Image
IHC-P analysis of human small intestine tissue using GTX17734 Elastin antibody [ELN/1981].
|
|
|
GTX17734 Protein Array Image
Analysis of Protein Array containing more than 19,000 full-length human proteins using Elastin (ELN) Mouse Monoclonal Antibody (ELN/1981). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
|
REFERENCE
There are currently no references for Elastin antibody [ELN/1981] (GTX17734). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Elastin antibody [ELN/1981] (GTX17734). Be the first to share your experience with this product.
![Anti-Elastin antibody [ELN/1981] used in IHC (Paraffin sections) (IHC-P). GTX17734](/upload/website/prouct_img/small/GTX17734/GTX17734_20200115_IHC-P_1149_w_23060620_895.webp "Anti-Elastin antibody [ELN/1981] used in IHC (Paraffin sections) (IHC-P). GTX17734")
![Anti-Elastin antibody [ELN/1981] used in Protein Array (Protein Array). GTX17734](/upload/website/prouct_img/small/GTX17734/GTX17734_20200115_Protein-Array_1935_w_23060620_764.webp "Anti-Elastin antibody [ELN/1981] used in Protein Array (Protein Array). GTX17734")
![Anti-Elastin antibody [ELN/1981] used in IHC (Paraffin sections) (IHC-P). GTX17734](/upload/website/prouct_img/normal/GTX17734/GTX17734_20200115_IHC-P_1149_w_23060620_895.webp "Anti-Elastin antibody [ELN/1981] used in IHC (Paraffin sections) (IHC-P). GTX17734")
![Anti-Elastin antibody [ELN/1981] used in Protein Array (Protein Array). GTX17734](/upload/website/prouct_img/normal/GTX17734/GTX17734_20200115_Protein-Array_1935_w_23060620_764.webp "Anti-Elastin antibody [ELN/1981] used in Protein Array (Protein Array). GTX17734")