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Elastin antibody [ELN/3131R]

Anti-Elastin antibody [ELN/3131R] used in IHC (Paraffin sections) (IHC-P). GTX02630
Anti-Elastin antibody [ELN/3131R] used in IHC (Paraffin sections) (IHC-P). GTX02630

Cat. No. GTX02630

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 ELN/3131R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Elastin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human Elastin protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

elastin , ADCL1 , SVAS , WBS , WS

Background

This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Elastin antibody [ELN/3131R] used in IHC (Paraffin sections) (IHC-P). GTX02630

GTX02630 IHC-P Image

IHC-P analysis of human small intestine tissue section using GTX02630 Elastin antibody [ELN/3131R].

Anti-Elastin antibody [ELN/3131R] used in IHC (Paraffin sections) (IHC-P). GTX02630

GTX02630 IHC-P Image

IHC-P analysis of human small intestine tissue section using GTX02630 Elastin antibody [ELN/3131R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529