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Endothelin 1 antibody [IC4]

Cat. No. GTX40940

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IC4

Isotype

 IgG1

Application

 IHC-Fr, IRMA

Reactivity

 Human
Package
100 μg ($399)
See all Endothelin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr Assay dependent
IRMA Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Product Note

Cross-Reactivity:Endothelin 1 100% Endothelin 3 ≤ 10%

PROPERTIES

Form

Liquid

Buffer

PBS pH7.6

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic Human Endothelin-1 C-Terminal Fragment

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endothelin 1 , ARCND3 , ET1 , HDLCQ7 , PPET1 , QME

Cellular Localization

Secreted

Background

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399