GeneTex
United States (US)

Endothelin 1 antibody

GTX37427_20190129_WB_19012901_327.jpg
GTX37427_20190129_ICCIF_19012901_945.jpg
GTX37427_20190129_ICCIF_1_19012901_536.jpg

Cat No. GTX37427

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:100-1000
ICC/IF 1:200
Not tested in other applications.

Calculated MW

24 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

10 mM PBS, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human Endothelin 1. Please contact us for the exact immunogen sequence.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Endothelin 1,Arcnd3,Et1,Hdlcq7,Ppet1,Qme,Edn1

Cellular Localization

Secreted

Background

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES
GTX37427_20190129_WB_19012901_327.jpg

GTX37427 WB Image

WB analysis of HeLa cells (Lane 1), mouse lung (Lane 2), rat heart (Lane 3), rat large intestines (Lane 4) lysates using GTX37427 Endothelin 1 antibody.
Dilution : 1μg/ml

GTX37427_20190129_ICCIF_19012901_945.jpg

GTX37427 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX37427 Endothelin 1 antibody.
Dilution : 2.5μg/ml

GTX37427_20190129_ICCIF_1_19012901_536.jpg

GTX37427 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX37427 Endothelin 1 antibody.
Dilution : 2.5μg/ml