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Endothelin A receptor antibody

Anti-Endothelin A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX12978

Cat No. GTX12978

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 3 - 16 μg/ml
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

Predict Reactivity

Mouse, Rabbit, Sheep, Bovine, Dog, Hamster, Chicken, Pig, Monkey, Bat, Gibbon, Gorilla, Horse, Marmoset, Opossum, Panda, Turkey, Platypus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from C-terminus of human Endothelin A Receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

endothelin receptor type A , EDNRA , ETA , ETAR , ETRA , MFDA , hETAR , Endothelin A Receptor

Cellular Localization

Cell membrane

Background

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Endothelin A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX12978

GTX12978 IHC-P Image

IHC-P analysis of human heart tissue using GTX12978 Endothelin A receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf