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Endothelin B Receptor antibody [C3], C-term

Anti-Endothelin B Receptor antibody [C3], C-term used in Western Blot (WB). GTX108204
Anti-Endothelin B Receptor antibody [C3], C-term used in Western Blot (WB). GTX108204

Cat. No. GTX108204

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Rat
Package
100 μl ($399),
25 μl ($169)
See all Endothelin B Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

A375 , Rat2

Predict Reactivity

Mouse, Rabbit, Bovine, Dog, Chicken, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.52 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human Endothelin B Receptor. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950161

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endothelin receptor type B , ABCDS , ET-B , ET-BR , ETB , ETB1 , ETBR , ETRB , HSCR , HSCR2 , WS4A

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Endothelin B Receptor antibody [C3], C-term used in Western Blot (WB). GTX108204

GTX108204 WB Image

Endothelin B Receptor antibody [C3], C-term detects EDNRB protein by western blot analysis.
A. 30 μg A375 whole cell lysate/extract
10% SDS-PAGE
Endothelin B Receptor antibody [C3], C-term (GTX108204) dilution: 1:500
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Endothelin B Receptor antibody [C3], C-term used in Western Blot (WB). GTX108204

GTX108204 WB Image

Endothelin B Receptor antibody [C3], C-term detects EDNRB protein by western blot analysis.
A. 30 μg Rat2 whole cell lysate/extract
10% SDS-PAGE
Endothelin B Receptor antibody [C3], C-term (GTX108204) dilution: 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

Application Reference

Xiao X et al. Environ Pollut 2016; Airborne fine particulate matter alters the expression of endothelin receptors in rat coronary arteries.
Application : WB
Reactivity : Rat
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169