APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
1:10-1:50 |
1:10-1:50 |
1:10-1:50 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rat, Rabbit, Bovine, Pig, Horse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human EDNRB.
Purification
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
endothelin receptor type B , ABCDS , ET-B , ET-BR , ETB , ETB1 , ETBR , ETRB , HSCR , HSCR2 , WS4A
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Database
Research Area
DATA IMAGES
|
GTX17408 IHC-P Image
IHC-P analysis of human prostate carcinoma using GTX17408 Endothelin B Receptor antibody.
|
|
GTX17408 WB Image
WB analysis of mouse cerebellum tissue lysate (35ug/lane) using GTX17408 Endothelin B Receptor antibody.
|
|
GTX17408 FACS Image
FACS analysis of MDA-MB435 cells using GTX17408 Endothelin B Receptor antibody. Top histogram : negative control Bottom histogram : MDA-MB435 cells
|
|
GTX17408 ICC/IF Image
ICC/IF analysis of 293 cells using GTX17408 Endothelin B Receptor antibody. Green : Endothelin B Receptor Blue : DAPI
|
REFERENCE
There are currently no references for Endothelin B Receptor antibody (GTX17408). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Endothelin B Receptor antibody (GTX17408). Be the first to share your experience with this product.