APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 |
1:50 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS pH7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human recombinant protein fragment corresponding to amino acids 24-265 of human EpCAM (NP_002345) produced in E.coli.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
epithelial cell adhesion molecule , DIAR5 , EGP-2 , EGP314 , EGP40 , ESA , HNPCC8 , KS1/4 , KSA , M4S1 , MIC18 , MK-1 , TACSTD1 , TROP1
Background
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Database
Research Area
DATA IMAGES
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GTX84572 WB Image
WB analysis of HEK293T cells transfected with EpCAM plasmid (Right) or empty vector (Left) for 48 hrs using GTX84572 EpCAM antibody [2C8]. Loading : 5 ug per lane
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GTX84572 IHC-P Image
IHC-P analysis of human lung carcinoma tissue using GTX84572 EpCAM antibody [2C8]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
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GTX84572 IHC-P Image
IHC-P analysis of human endometrium tissue using GTX84572 EpCAM antibody [2C8]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
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GTX84572 WB Image
WB analysis of various cell lines using GTX84572 EpCAM antibody [2C8]. Loading : 35 ug per lane
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GTX84572 IHC-P Image
IHC-P analysis of human liver tissue using GTX84572 EpCAM antibody [2C8]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
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GTX84572 IHC-P Image
IHC-P analysis of human kidney tissue using GTX84572 EpCAM antibody [2C8]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
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GTX84572 IHC-P Image
IHC-P analysis of human colon adenocarcinoma tissue using GTX84572 EpCAM antibody [2C8]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
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REFERENCE
There are currently no references for EpCAM antibody [2C8] (GTX84572). Be the first to share your publications with this product.
REVIEW
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